Night-time cough recording app predicts asthma deterioration

The app is the first of its kind to measure patients’ coughing over a series of nights and shows that it is a sign of their asthma deteriorating.

The team, led by Dr Frank Rassouli, from the Cantonal Hospital St Gallen, Switzerland, believe it could become a new way to help patients and their doctors monitor asthma and adjust medication to keep symptoms under control.

“Until now, we haven’t had a reliable tool for measuring peoples’ asthma symptoms overnight, so we know very little about night-time coughing and what it means,” Rassouli said.

“The current focus of our research group is using technology and simple interventions to improve the management of chronic lung diseases like asthma and chronic obstructive pulmonary disease.

“Smartphones have lots of potential to monitor different symptoms and detect changes early, so we worked with our research partners from University of St. Gallen and ETH Zurich to develop an app for measuring coughing.”

The study involved 94 asthma patients who were being treated at two clinics in Switzerland. Each patient visited their asthma clinic at the beginning and end of the study and were assessed for their use of asthma treatments, symptoms such as shortness of breath and whether their asthma had any impact on their daily life.

For 29 days in between they slept with a smartphone in their bedroom with the app running that measured the noise of their night-time coughing. The app also prompted patients to report their night-time symptoms.

The researchers found that the amount of night-time coughing varied a lot from one patient to the next, but there was a strong correlation between an increase in night-time coughing over the course of a week and a subsequent worsening of asthma symptoms.

Dr Rassouli said: “Our results suggest that night-time coughing can be measured fairly simply with a smartphone app and that an increase in coughing at night is an indicator that asthma is deteriorating. Monitoring asthma is really important because if we can spot early signs that it’s getting worse, we can adjust medication to prevent asthma attacks.”

The team is also planning to try the same technology out with people who have chronic obstructive pulmonary disease.

Thierry Troosters, president of the European Respiratory Society, said: “Asthma is a common condition, affecting millions of people in Europe alone. It cannot be cured, but by ensuring that patients use their treatments as prescribed by their doctors, asthma can usually be well-controlled. Uncontrolled asthma can interfere with school or work and lead to serious asthma attacks.

“This study offers a potential new way to monitor patients for signs that their asthma might be getting worse, and the fact that it works via a smartphone makes it accessible to most patients.”


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